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Cathepsin L Participates in the Production of Neuropeptide Y in Secretory Vesicles, Demonstrated by Protease Gene Knockout and Expression
Neuropeptide Y (NPY) functions as a peptide neurotransmitter and as a neuroendocrine hormone. The active NPY peptide is generated in secretory vesicles by proteolytic processing of proNPY. Novel findings from this study show that cathepsin L participates as a key proteolytic enzyme for NPY productio...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2661760/ https://ncbi.nlm.nih.gov/pubmed/18410501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2008.05408.x |
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