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The endocytic pathway mediates cell entry of dsRNA to induce RNAi silencing
Many metazoan cells can take up exogenous double-stranded (ds) RNA and use it to initiate an RNA silencing response, however, the mechanism for this uptake is ill-defined. Here, we identify the pathway for dsRNA uptake in Drosophila melanogaster S2 cells. Biochemical and cell biological analyses, an...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2731564/ https://ncbi.nlm.nih.gov/pubmed/16862146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncbl439 |
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