Systems-Level Modeling of Cancer-Fibroblast Interaction

Cancer cells interact with surrounding stromal fibroblasts during tumorigenesis, but the complex molecular rules that govern these interactions remain poorly understood thus hindering the development of therapeutic strategies to target cancer stroma. We have taken a mathematical approach to begin de...

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Detalhes bibliográficos
Main Authors: Wadlow, Raymond C., Wittner, Ben S., Finley, S. Aidan, Bergquist, Henry, Upadhyay, Rabi, Finn, Stephen, Loda, Massimo, Mahmood, Umar, Ramaswamy, Sridhar
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731225/
https://ncbi.nlm.nih.gov/pubmed/19727395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006888
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