Systems-Level Modeling of Cancer-Fibroblast Interaction

Cancer cells interact with surrounding stromal fibroblasts during tumorigenesis, but the complex molecular rules that govern these interactions remain poorly understood thus hindering the development of therapeutic strategies to target cancer stroma. We have taken a mathematical approach to begin de...

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Hlavní autoři: Wadlow, Raymond C., Wittner, Ben S., Finley, S. Aidan, Bergquist, Henry, Upadhyay, Rabi, Finn, Stephen, Loda, Massimo, Mahmood, Umar, Ramaswamy, Sridhar
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2009
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731225/
https://ncbi.nlm.nih.gov/pubmed/19727395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006888
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