Genetically engineered T cells to target EGFRvIII expressing glioblastoma

Glioblastoma remains a significant therapeutic challenge, warranting further investigation of novel therapies. We describe an immunotherapeutic strategy to treat glioblastoma based on adoptive transfer of genetically modified T-lymphocytes (T cells) redirected to kill EGFRvIII expressing gliomas. We...

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Bibliografiske detaljer
Main Authors: Bullain, Szofia S., Sahin, Ayguen, Szentirmai, Oszkar, Sanchez, Carlos, Lin, Ning, Baratta, Elizabeth, Waterman, Peter, Weissleder, Ralph, Mulligan, Richard C., Carter, Bob S.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730985/
https://ncbi.nlm.nih.gov/pubmed/19387557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-009-9889-1
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