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Association of Botulinum neurotoxins with synaptic vesicle protein complexes

Botulinum neurotoxins (BoNTs) elicit flaccid paralysis by cleaving SNARE proteins within peripheral neurons. BoNTs are classified into seven serotypes, termed A-G, based upon antibody cross neutralization. Clostridia produce BoNTs are single chain toxins that are cleaved into a di-chain protein that...

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Detalhes bibliográficos
Main Authors: Baldwin, Michael R, Barbieri, Joseph T
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730980/
https://ncbi.nlm.nih.gov/pubmed/19362106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxicon.2009.01.040
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