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Absence of ubiquitinated inclusions in hypocretin neurons of patients with narcolepsy

OBJECTIVES: The cause of hypocretin cell loss in human narcolepsy–cataplexy is unknown but has been suggested to be neurodegenerative in nature. To test this hypothesis, we evaluated the remaining hypocretin cells in human narcolepsy brains for the presence of aggregated protein inclusions, gliosis,...

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Detalhes bibliográficos
Main Authors: Honda, M, Arai, T, Fukazawa, M, Honda, Y, Tsuchiya, K, Salehi, A, Akiyama, H, Mignot, E
Formato: Artigo
Idioma:Inglês
Publicado em: American Academy of Neurology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730798/
https://ncbi.nlm.nih.gov/pubmed/19687452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e3181b2a6af
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