TLR2 and its co-receptors determine responses of macrophages and dendritic cells to lipoproteins of Mycobacterium tuberculosis

Mycobacterium tuberculosis (Mtb) signals through Toll-like receptor 2 (TLR2) to regulate antigen presenting cells (APCs). Mtb lipoproteins, including LpqH, LprA, LprG and PhoS1, are TLR2 agonists, but their co-receptor requirements are unknown. We studied Mtb lipoprotein-induced responses in TLR2(−/...

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Detalhes bibliográficos
Main Authors: Drage, Michael G., Pecora, Nicole D., Hise, Amy G., Febbraio, Maria, Silverstein, Roy L., Golenbock, Douglas T., Boom, W. Henry, Harding, Clifford V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730726/
https://ncbi.nlm.nih.gov/pubmed/19362712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2009.03.008
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