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Discovery and Structural Analysis of Eph Receptor Tyrosine Kinase Inhibitors

The Eph family of receptor tyrosine kinases has drawn growing attention due to their role in regulating diverse biological phenomena. However, pharmacological interrogation of Eph kinase function has been hampered by a lack of potent and selective Eph kinase inhibitors. Here we report the discovery...

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Détails bibliographiques
Auteurs principaux: Choi, Yongmun, Syeda, Farisa, Walker, John R., Finerty, Patrick J., Cuerrier, Dominic, Wojciechowski, Amy, Liu, Qingsong, Dhe-Paganon, Sirano, Gray, Nathanael S.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730633/
https://ncbi.nlm.nih.gov/pubmed/19553108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2009.05.029
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