Discovery and Structural Analysis of Eph Receptor Tyrosine Kinase Inhibitors

The Eph family of receptor tyrosine kinases has drawn growing attention due to their role in regulating diverse biological phenomena. However, pharmacological interrogation of Eph kinase function has been hampered by a lack of potent and selective Eph kinase inhibitors. Here we report the discovery...

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Main Authors: Choi, Yongmun, Syeda, Farisa, Walker, John R., Finerty, Patrick J., Cuerrier, Dominic, Wojciechowski, Amy, Liu, Qingsong, Dhe-Paganon, Sirano, Gray, Nathanael S.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730633/
https://ncbi.nlm.nih.gov/pubmed/19553108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2009.05.029
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