Discovery of a Potent and Selective DDR1 Receptor Tyrosine Kinase Inhibitor

[Image: see text] The DDR1 receptor tyrosine kinase is activated by matrix collagens and has been implicated in numerous cellular functions such as proliferation, differentiation, adhesion, migration, and invasion. Here we report the discovery of a potent and selective DDR1 inhibitor, DDR1-IN-1, and...

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Detalhes bibliográficos
Main Authors: Kim, Hyung-Gu, Tan, Li, Weisberg, Ellen L., Liu, Feiyang, Canning, Peter, Choi, Hwan Geun, Ezell, Scott A., Wu, Hong, Zhao, Zheng, Wang, Jinhua, Mandinova, Anna, Griffin, James D., Bullock, Alex N., Liu, Qingsong, Lee, Sam W., Gray, Nathanael S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2013
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3800496/
https://ncbi.nlm.nih.gov/pubmed/23899692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb400430t
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