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Submicromolar concentrations of 4-hydroxynonenal induce glutamate cysteine ligase expression in HBE1 cells

4-Hydroxynonenal (HNE), a major electrophilic product of lipid peroxidation, is regarded as both a marker of oxidative stress and a mediator of oxidative damage. At subtoxic concentrations, however, this compound has been shown to be a signalling molecule that can induce the expression of various an...

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Библиографические подробности
Главные авторы: Zhang, Hongqiao, Court, Nathalie, Forman, Henry Jay
Формат: Artigo
Язык:Inglês
Опубликовано: 2007
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730489/
https://ncbi.nlm.nih.gov/pubmed/17263920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1179/135100007X162266
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