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Xenopus oocytes reactivate muscle gene transcription in transplanted somatic nuclei independently of myogenic factors

Transplantation into eggs or oocytes is an effective means of achieving the reprogramming of somatic cell nuclei. We ask here whether the provision of gene-specific transcription factors forms part of the mechanism by which a gene that is repressed in somatic cells is transcribed in oocytes. We find...

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Hlavní autoři: Biddle, Adrian, Simeoni, Ilenia, Gurdon, J. B.
Médium: Artigo
Jazyk:Inglês
Vydáno: Company of Biologists 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730400/
https://ncbi.nlm.nih.gov/pubmed/19605498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.036327
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