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Xenopus oocytes reactivate muscle gene transcription in transplanted somatic nuclei independently of myogenic factors

Transplantation into eggs or oocytes is an effective means of achieving the reprogramming of somatic cell nuclei. We ask here whether the provision of gene-specific transcription factors forms part of the mechanism by which a gene that is repressed in somatic cells is transcribed in oocytes. We find...

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Autores principales: Biddle, Adrian, Simeoni, Ilenia, Gurdon, J. B.
Formato: Artigo
Lenguaje:Inglês
Publicado: Company of Biologists 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730400/
https://ncbi.nlm.nih.gov/pubmed/19605498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.036327
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