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Prothrombin amino terminal region helps protect coagulation factor Va from proteolytic inactivation by activated protein C
The hypothesis that prothrombin (FII) protects coagulation factor Va (FVa) from proteolytic inactivation by activated protein C (APC) was tested using purified proteins. FII dose-dependently protected FVa from APC proteolysis under conditions where competition of proteins for binding to negatively-c...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2730196/ https://ncbi.nlm.nih.gov/pubmed/19132189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH08-07-0491 |
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