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Blood coagulation factor Va's key interactive residues and regions for prothrombinase assembly and prothrombin binding
Blood coagulation factor Va serves an indispensable role in hemostasis as cofactor for the serine protease factor Xa. In the presence of an anionic phospholipid membrane and calcium ions, factors Va and Xa assemble into the prothrombinase complex. Following formation of the ternary complex with the...
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| Pubblicato in: | J Thromb Haemost |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6851895/ https://ncbi.nlm.nih.gov/pubmed/31102425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.14487 |
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