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Blood coagulation factor Va's key interactive residues and regions for prothrombinase assembly and prothrombin binding

Blood coagulation factor Va serves an indispensable role in hemostasis as cofactor for the serine protease factor Xa. In the presence of an anionic phospholipid membrane and calcium ions, factors Va and Xa assemble into the prothrombinase complex. Following formation of the ternary complex with the...

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Bibliografski detalji
Izdano u:J Thromb Haemost
Glavni autori: Schreuder, Mark, Reitsma, Pieter H., Bos, Mettine H. A.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6851895/
https://ncbi.nlm.nih.gov/pubmed/31102425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.14487
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