Plasma protein S residues 37–50 mediate its binding to factor Va and inhibition of blood coagulation

Protein S (PS) is an anticoagulant plasma protein whose deficiency is associated with increased risk of venous thrombosis. PS directly inhibits thrombin generation by the blood coagulation pathways by several mechanisms, including by binding coagulation factors (F) Va and Xa. To identify PS sequence...

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Bibliografiska uppgifter
Huvudupphovsmän: Heeb, Mary J., Mesters, Rolf M., Fernández, José A., Hackeng, Tilman M., Nakasone, Ryon K., Griffin, John H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733499/
https://ncbi.nlm.nih.gov/pubmed/23892573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH12-12-0953
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