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Plasma protein S residues 37–50 mediate its binding to factor Va and inhibition of blood coagulation

Protein S (PS) is an anticoagulant plasma protein whose deficiency is associated with increased risk of venous thrombosis. PS directly inhibits thrombin generation by the blood coagulation pathways by several mechanisms, including by binding coagulation factors (F) Va and Xa. To identify PS sequence...

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Detalhes bibliográficos
Main Authors: Heeb, Mary J., Mesters, Rolf M., Fernández, José A., Hackeng, Tilman M., Nakasone, Ryon K., Griffin, John H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733499/
https://ncbi.nlm.nih.gov/pubmed/23892573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH12-12-0953
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