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A Concise Asymmetric Synthesis of cis-2,6-Disubstituted N-Aryl Piperazines via Pd-Catalyzed Carboamination Reactions
[Image: see text] A concise, modular, asymmetric synthesis of cis-2,6-disubstituted piperazines from readily available amino acid precursors is described. The key step in the synthesis is a Pd-catalyzed carboamination of a N(1-)aryl-N(2)-allyl-1,2-diamine with an aryl bromide. The products are obtai...
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| Hoofdauteurs: | , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2007
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2730114/ https://ncbi.nlm.nih.gov/pubmed/17650007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol071241f |
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