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Circadian Dysregulation Disrupts Bile Acid Homeostasis

BACKGROUND: Bile acids are potentially toxic compounds and their levels of hepatic production, uptake and export are tightly regulated by many inputs, including circadian rhythm. We tested the impact of disrupting the peripheral circadian clock on integral steps of bile acid homeostasis. METHODOLOGY...

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Bibliografiske detaljer
Main Authors: Ma, Ke, Xiao, Rui, Tseng, Hsiu-Ting, Shan, Lu, Fu, Loning, Moore, David D.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730029/
https://ncbi.nlm.nih.gov/pubmed/19718444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006843
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