Utilization of Genomic Signatures to Identify Phenotype-Specific Drugs

Genetic and genomic studies highlight the substantial complexity and heterogeneity of human cancers and emphasize the general lack of therapeutics that can match this complexity. With the goal of expanding opportunities for drug discovery, we describe an approach that makes use of a phenotype-based...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mori, Seiichi, Chang, Jeffrey T., Andrechek, Eran R., Potti, Anil, Nevins, Joseph R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2009
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729377/
https://ncbi.nlm.nih.gov/pubmed/19714244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006772
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