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Genetic heterogeneity of Myc-induced mammary tumors reflecting diverse phenotypes including metastatic potential

Human cancers result from a complex series of genetic alterations, resulting in heterogeneous disease states. Dissecting this heterogeneity is critical for understanding underlying mechanisms and providing opportunities for therapeutics matching the complexity. Mouse models of cancer have generally...

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Detalhes bibliográficos
Main Authors: Andrechek, Eran R., Cardiff, Robert D., Chang, Jeffrey T., Gatza, Michael L., Acharya, Chaitanya R., Potti, Anil, Nevins, Joseph R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752567/
https://ncbi.nlm.nih.gov/pubmed/19805309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901250106
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