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Utilization of Genomic Signatures to Identify Phenotype-Specific Drugs

Genetic and genomic studies highlight the substantial complexity and heterogeneity of human cancers and emphasize the general lack of therapeutics that can match this complexity. With the goal of expanding opportunities for drug discovery, we describe an approach that makes use of a phenotype-based...

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Detalhes bibliográficos
Main Authors: Mori, Seiichi, Chang, Jeffrey T., Andrechek, Eran R., Potti, Anil, Nevins, Joseph R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729377/
https://ncbi.nlm.nih.gov/pubmed/19714244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006772
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