CD4(+)CD25(−)LAG3(+) regulatory T cells controlled by the transcription factor Egr-2

Regulatory T cells (Tregs) are engaged in the maintenance of immunological self-tolerance and immune homeostasis. IL-10 has an important role in maintaining the normal immune state. Here, we show that IL-10-secreting Tregs can be delineated in normal mice as CD4(+)CD25(−)Foxp3(−) T cells that expres...

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Autori principali: Okamura, Tomohisa, Fujio, Keishi, Shibuya, Mihoko, Sumitomo, Shuji, Shoda, Hirofumi, Sakaguchi, Shimon, Yamamoto, Kazuhiko
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2009
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729005/
https://ncbi.nlm.nih.gov/pubmed/19666526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906872106
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