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Crystal structure of the sodium-potassium pump (Na(+),K(+)-ATPase) with bound potassium and ouabain

The sodium-potassium pump (Na(+),K(+)-ATPase) is responsible for establishing Na(+) and K(+) concentration gradients across the plasma membrane and therefore plays an essential role in, for instance, generating action potentials. Cardiac glycosides, prescribed for congestive heart failure for more t...

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Detalhes bibliográficos
Main Authors: Ogawa, Haruo, Shinoda, Takehiro, Cornelius, Flemming, Toyoshima, Chikashi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728964/
https://ncbi.nlm.nih.gov/pubmed/19666591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907054106
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