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Antiepileptic effects of silk-polymer based adenosine release in kindled rats

Pharmacotherapy for epilepsy is limited by high incidence of pharmacoresistance and failure to prevent development and progression of epilepsy. Using the rat hippocampal kindling model, we report on the therapeutic potential of novel silk-based polymers engineered to release the anticonvulsant adeno...

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Bibliografiske detaljer
Main Authors: Szybala, Cory, Pritchard, Eleanor M., Lusardi, Theresa A., Li, Tianfu, Wilz, Andrew, Kaplan, David L., Boison, Detlev
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728789/
https://ncbi.nlm.nih.gov/pubmed/19460372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2009.05.018
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