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Grafts of adenosine-releasing cells suppress seizures in kindling epilepsy
Adenosine is an inhibitor of neuronal activity in the brain. The local release of adenosine from grafted cells was evaluated as an ex vivo gene therapy approach to suppress synchronous discharges and epileptic seizures. Fibroblasts were engineered to release adenosine by inactivating the adenosine-m...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC34716/ https://ncbi.nlm.nih.gov/pubmed/11404469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.131102898 |
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