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Antiepileptic effects of silk-polymer based adenosine release in kindled rats

Pharmacotherapy for epilepsy is limited by high incidence of pharmacoresistance and failure to prevent development and progression of epilepsy. Using the rat hippocampal kindling model, we report on the therapeutic potential of novel silk-based polymers engineered to release the anticonvulsant adeno...

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Autori principali: Szybala, Cory, Pritchard, Eleanor M., Lusardi, Theresa A., Li, Tianfu, Wilz, Andrew, Kaplan, David L., Boison, Detlev
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728789/
https://ncbi.nlm.nih.gov/pubmed/19460372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2009.05.018
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