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Antiepileptic effects of silk-polymer based adenosine release in kindled rats
Pharmacotherapy for epilepsy is limited by high incidence of pharmacoresistance and failure to prevent development and progression of epilepsy. Using the rat hippocampal kindling model, we report on the therapeutic potential of novel silk-based polymers engineered to release the anticonvulsant adeno...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2728789/ https://ncbi.nlm.nih.gov/pubmed/19460372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2009.05.018 |
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