Cell Shape and Negative Links in Regulatory Motifs Together Control Spatial Information Flow in Signaling Networks

The role of cell size and shape in controlling local intracellular signaling reactions, and how this spatial information originates and is propagated, is not well understood. We have used partial differential equations to model the flow of spatial information from the β-adrenergic receptor to MAPK1,...

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Bibliografiske detaljer
Main Authors: Neves, Susana R., Tsokas, Panayiotis, Sarkar, Anamika, Grace, Elizabeth A., Rangamani, Padmini, Taubenfeld, Stephen M., Alberini, Cristina M., Schaff, James C., Blitzer, Robert D., Moraru, Ion I., Iyengar, Ravi
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728678/
https://ncbi.nlm.nih.gov/pubmed/18485874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.04.025
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