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Mitogen-Activated Protein Kinase Upregulates the Dendritic Translation Machinery in Long-Term Potentiation by Controlling the Mammalian Target of Rapamycin Pathway

Protein synthesis is required for persistent forms of synaptic plasticity, including long-term potentiation (LTP). A key regulator of LTP-related protein synthesis is mammalian target of rapamycin (mTOR), which is thought to modulate translational capacity by facilitating the synthesis of particular...

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Опубликовано в: :J Neurosci
Главные авторы: Tsokas, Panayiotis, Ma, Tao, Iyengar, Ravi, Landau, Emmanuel M., Blitzer, Robert D.
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Neuroscience 2007
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672260/
https://ncbi.nlm.nih.gov/pubmed/17537959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4548-06.2007
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