Cell Shape and Negative Links in Regulatory Motifs Together Control Spatial Information Flow in Signaling Networks

The role of cell size and shape in controlling local intracellular signaling reactions, and how this spatial information originates and is propagated, is not well understood. We have used partial differential equations to model the flow of spatial information from the β-adrenergic receptor to MAPK1,...

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Detalhes bibliográficos
Main Authors: Neves, Susana R., Tsokas, Panayiotis, Sarkar, Anamika, Grace, Elizabeth A., Rangamani, Padmini, Taubenfeld, Stephen M., Alberini, Cristina M., Schaff, James C., Blitzer, Robert D., Moraru, Ion I., Iyengar, Ravi
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728678/
https://ncbi.nlm.nih.gov/pubmed/18485874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.04.025
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