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A necessary role of miR-221 and miR-222 in vascular smooth muscle cell proliferation and neointimal hyperplasia

MicroRNAs comprise a novel class of endogenous, small, noncoding RNAs that negatively regulate gene expression. Functionally, an individual miRNA is as important as a transcription factor because it is able to regulate the expression of its multiple target genes. Recently, miR-221 and miR-222 have b...

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Hlavní autoři: Liu, Xiaojun, Cheng, Yunhui, Zhang, Shuo, Lin, Ying, Yang, Jian, Zhang, Chunxiang
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728290/
https://ncbi.nlm.nih.gov/pubmed/19150885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.185363
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