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Highly transcribed RNA polymerase II genes are impediments to replication fork progression in Saccharomyces cerevisiae
Replication forks face multiple obstacles that slow their progression. By two-dimensional gel analysis, yeast forks pause at stable DNA protein complexes, and this pausing is greatly increased in the absence of the Rrm3 helicase. We used a genome wide approach to identify 96 sites of very high DNA p...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2728070/ https://ncbi.nlm.nih.gov/pubmed/19560424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.05.022 |
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