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CD8(+) T cell immunodominance shifts during the early stages of acute LCMV infection independently from functional avidity maturation

Virus-specific T cell responses are often directed to a small subset of possible epitopes and their relative magnitude defines their hierarchy. We determined the size and functional avidity of 4 representative peptide-specific CD8(+) T cell populations in C57BL/6 mice at different time points after...

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Main Authors: Raué, Hans-Peter, Slifka, Mark K.
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728041/
https://ncbi.nlm.nih.gov/pubmed/19539966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.05.021
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