The epithelial-mesenchymal transition generates cells with properties of stem cells

The epithelial-mesenchymal transition (EMT) is a key developmental program that is often activated during cancer invasion and metastasis. Induction of an EMT in immortalized human mammary epithelial cells (HMLEs) results in the acquisition of mesenchymal traits, but in addition the expression of ste...

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Autors principals: Mani, Sendurai A., Guo, Wenjun, Liao, Mai-Jing, Eaton, Elinor Ng., Ayyanan, Ayyakkannu, Zhou, Alicia Y., Brooks, Mary, Reinhard, Ferenc, Zhang, Cheng Cheng, Shipitsin, Michail, Campbell, Lauren L., Polyak, Kornelia, Brisken, Cathrin, Yang, Jing, Weinberg, Robert A.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728032/
https://ncbi.nlm.nih.gov/pubmed/18485877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.03.027
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