The epithelial-mesenchymal transition generates cells with properties of stem cells

The epithelial-mesenchymal transition (EMT) is a key developmental program that is often activated during cancer invasion and metastasis. Induction of an EMT in immortalized human mammary epithelial cells (HMLEs) results in the acquisition of mesenchymal traits, but in addition the expression of ste...

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Detalhes bibliográficos
Main Authors: Mani, Sendurai A., Guo, Wenjun, Liao, Mai-Jing, Eaton, Elinor Ng., Ayyanan, Ayyakkannu, Zhou, Alicia Y., Brooks, Mary, Reinhard, Ferenc, Zhang, Cheng Cheng, Shipitsin, Michail, Campbell, Lauren L., Polyak, Kornelia, Brisken, Cathrin, Yang, Jing, Weinberg, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728032/
https://ncbi.nlm.nih.gov/pubmed/18485877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.03.027
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