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Dopamine modulates an intrinsic mGluR5-mediated depolarization underlying prefrontal persistent activity

Intrinsic properties of neurons that enable them to maintain depolarized, persistently activated states in the absence of sustained input are poorly understood. In short-term memory tasks, individual prefrontal cortical (PFC) neurons are capable of maintaining persistent action potential output duri...

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Detalhes bibliográficos
Main Authors: Sidiropoulou, Kyriaki, Lu, Fang-Min, Fowler, Melissa A., Xiao, Rui, Phillips, Christopher, Ozkan, Emin D., Zhu, Michael X., White, Francis J., Cooper, Donald C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2727588/
https://ncbi.nlm.nih.gov/pubmed/19169252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2245
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