Thymic output, T-cell diversity, and T-cell function in long-term human SCID chimeras

Severe combined immunodeficiency (SCID) is a syndrome of diverse genetic cause characterized by profound deficiencies of T, B, and sometimes NK-cell function. Nonablative human leukocyte antigen–identical or rigorously T cell–depleted haploidentical parental bone marrow transplantation (BMT) results...

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Détails bibliographiques
Auteurs principaux: Sarzotti-Kelsoe, Marcella, Win, Chan M., Parrott, Roberta E., Cooney, Myriah, Moser, Barry K., Roberts, Joseph L., Sempowski, Gregory D., Buckley, Rebecca H.
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2009
Sujets:
Transplantation
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2727406/
https://ncbi.nlm.nih.gov/pubmed/19433858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-01-199323
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