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T(−)B(+)NK(+) severe combined immunodeficiency caused by complete deficiency of the CD3ζ subunit of the T-cell antigen receptor complex
CD3ζ is a subunit of the T-cell antigen receptor (TCR) complex required for its assembly and surface expression that also plays an important role in TCR-mediated signal transduction. We report here a patient with T(−)B(+)NK(+) severe combined immunodeficiency (SCID) who was homozygous for a single C...
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| Main Authors: | , , , , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society of Hematology
2007
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1852234/ https://ncbi.nlm.nih.gov/pubmed/17170122 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-08-043166 |
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