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Lentiviral Vectors with Amplified Beta Cell-Specific Gene Expression

An important goal of gene therapy is to be able to deliver genes so that they express in a pattern that recapitulates the expression of an endogenous cellular gene. Although tissue-specific promoters confer selectivity, in a vector-based system, their activity may be too weak to mediate detectable l...

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Detalhes bibliográficos
Main Authors: Shaw, Kit L., Pais, Eszter, Ge, Shundi, Hardee, Cinnamon, Skelton, Dianne, Hollis, Roger, Crooks, Gay M., Kohn, Donald B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726899/
https://ncbi.nlm.nih.gov/pubmed/19440227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2009.49
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