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Electrical remodeling contributes to complex tachyarrhythmias in connexin43-deficient mouse hearts
Loss of connexin43 (Cx43) gap junction channels in the heart results in a marked increase in the incidence of spontaneous and inducible polymorphic ventricular tachyarrhythmias (PVTs). The mechanisms resulting in this phenotype remain unclear. We hypothesized that uncoupling promotes regional ion ch...
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Autori principali: | , , , , , |
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Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
2007
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2726820/ https://ncbi.nlm.nih.gov/pubmed/17984180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.07-8974com |
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