Decreased connexin43 expression in the mouse heart potentiates pacing-induced remodeling of repolarizing currents

Gap junction redistribution and reduced expression, a phenomenon termed gap junction remodeling (GJR), is often seen in diseased hearts and may predispose toward arrhythmias. We have recently shown that short-term pacing in the mouse is associated with changes in connexin43 (Cx43) expression and loc...

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Main Authors: Kontogeorgis, Andrianos, Li, Xiaodong, Kang, Eunice Y., Feig, Jonathan E., Ponzio, Marc, Kang, Guoxin, Kaba, Riyaz A., Wit, Andrew L., Fisher, Edward A., Morley, Gregory E., Peters, Nicholas S., Coetzee, William A., Gutstein, David E.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2008
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614590/
https://ncbi.nlm.nih.gov/pubmed/18757477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.590.2008
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