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Reduced intercellular coupling leads to paradoxical propagation across the Purkinje-ventricular junction and aberrant myocardial activation

Ventricular tachycardia is a common heart rhythm disorder and a frequent cause of sudden cardiac death. Aberrant cell–cell coupling through gap junction channels, a process termed gap junction remodeling, is observed in many of the major forms of human heart disease and is associated with increased...

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Detalhes bibliográficos
Main Authors: Morley, Gregory E., Danik, Stephan B., Bernstein, Scott, Sun, Yanjie, Rosner, Gregg, Gutstein, David E., Fishman, Glenn I.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC554832/
https://ncbi.nlm.nih.gov/pubmed/15753312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500881102
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