Electrical remodeling contributes to complex tachyarrhythmias in connexin43-deficient mouse hearts

Loss of connexin43 (Cx43) gap junction channels in the heart results in a marked increase in the incidence of spontaneous and inducible polymorphic ventricular tachyarrhythmias (PVTs). The mechanisms resulting in this phenotype remain unclear. We hypothesized that uncoupling promotes regional ion ch...

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Bibliographic Details
Main Authors: Danik, Stephan B., Rosner, Gregg, Lader, Joshua, Gutstein, David E., Fishman, Glenn I., Morley, Gregory E.
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726820/
https://ncbi.nlm.nih.gov/pubmed/17984180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.07-8974com
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