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Sepsis-induced human lymphocyte apoptosis and cytokine production in “humanized” mice

Sepsis is the leading cause of death in critically ill patients in the United States with over 210,000 deaths annually. One stumbling block to an effective therapy of sepsis has been the lack of a clinically relevant animal model. There are important distinctions in the mouse versus human immune sys...

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Detalhes bibliográficos
Main Authors: Unsinger, Jacqueline, McDonough, Jacquelyn S., Shultz, Leonard D., Ferguson, Thomas A., Hotchkiss, Richard S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Society for Leukocyte Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726769/
https://ncbi.nlm.nih.gov/pubmed/19369639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1008615
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