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Liver X receptor agonist regulation of Th17 lymphocyte function in autoimmunity

CD4(+) Th17 cells are believed to play an important role in the development of a variety of autoimmune diseases including EAE, an animal model of MS. Previously, we and others demonstrated that LXR agonists suppressed the activation of primary glial cells and blocked the development of EAE. The pres...

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Autores principales: Xu, Jihong, Wagoner, Gail, Douglas, James C., Drew, Paul D.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Society for Leukocyte Biology 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726767/
https://ncbi.nlm.nih.gov/pubmed/19406833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1008600
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