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In Vivo Analysis of the Notch Receptor S1 Cleavage

A ligand-independent cleavage (S1) in the extracellular domain of the mammalian Notch receptor results in what is considered to be the canonical heterodimeric form of Notch on the cell surface. The in vivo consequences and significance of this cleavage on Drosophila Notch signaling remain unclear an...

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Bibliografiska uppgifter
Huvudupphovsmän: Lake, Robert J., Grimm, Lisa M., Veraksa, Alexey, Banos, Andrew, Artavanis-Tsakonas, Spyros
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726433/
https://ncbi.nlm.nih.gov/pubmed/19701455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006728
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