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Sequence Dependencies of DNA Deformability and Hydration in the Minor Groove

DNA deformability and hydration are both sequence-dependent and are essential in specific DNA sequence recognition by proteins. However, the relationship between the two is not well understood. Here, systematic molecular dynamics simulations of 136 DNA sequences that differ from each other in their...

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Bibliographic Details
Main Authors: Yonetani, Yoshiteru, Kono, Hidetoshi
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726331/
https://ncbi.nlm.nih.gov/pubmed/19686662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.05.049
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