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Atomistic View of the Conformational Activation of Src Kinase Using the String Method with Swarms-of-Trajectories
The inactive-to-active conformational transition of the catalytic domain of human c-Src tyrosine kinase is characterized using the string method with swarms-of-trajectories with all-atom explicit solvent molecular dynamics simulations. The activation process occurs in two main steps in which the act...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2726321/ https://ncbi.nlm.nih.gov/pubmed/19686639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.06.016 |
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