Vulnerability to (+)-Methamphetamine Effects and the Relationship to Drug Disposition in Pregnant Rats during Chronic Infusion

Chronic (+)-methamphetamine (METH) use during pregnancy increases the health risk for both mother and fetus. To provide insights into these risks, the relationship between changes in METH disposition and METH-induced pharmacological effects were studied in Sprague-Dawley rat dams and litters. Timed-...

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Hlavní autoři: White, Sarah J., Laurenzana, Elizabeth M., Gentry, William Brooks, Hendrickson, Howard P., Williams, David Keith, Ward, Keith W., Owens, Samuel Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2009
Témata:
Biotransformation and Toxicokinetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726297/
https://ncbi.nlm.nih.gov/pubmed/19520673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfp127
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