ADAMTS1 and MMP1 proteolytically engage EGF-like ligands in an osteolytic signaling cascade for bone metastasis

Bone metastasis is mediated by complex interactions between tumor cells and resident stromal cells in the bone microenvironment. The functions of metalloproteinases in organ-specific metastasis remain poorly defined despite their well-appreciated role in matrix degradation and tumor invasion. Here,...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Lu, Xin, Wang, Qiongqing, Hu, Guohong, Van Poznak, Catherine, Fleisher, Martin, Reiss, Michael, Massagué, Joan, Kang, Yibin
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2009
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2725946/
https://ncbi.nlm.nih.gov/pubmed/19608765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1824809
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares